Successful Treatment of Pyoderma Gangrenosum with Prednisolone, Cyclosporine, and Dapsone.
- Author:
Kyong Tae KIM
1
;
Chi Yeon KIM
;
Tae Jin YOON
Author Information
1. Department of Dermatology, College of Medicine, Gyeongsang National University, Jinju, Korea. jaymax1@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Cyclosporine;
Dapsone;
Pyoderma gangrenosum
- MeSH:
Adrenal Cortex Hormones;
Cyclosporine*;
Dapsone*;
Diagnosis;
Female;
Humans;
Immunomodulation;
Prednisolone*;
Pyoderma Gangrenosum*;
Pyoderma*;
Ulcer
- From:Korean Journal of Dermatology
2006;44(3):372-374
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pyoderma gangrenosum is an uncommon, chronic, recurrent cutaneous ulcerative disease. It is difficult to diagnosis and is frequently associated with systemic diseases. There is no specific therapy, nor effective uniform therapy. Systemic treatment with corticosteroids or cyclosporine, alone or together, appeared to be effective in many cases. However, prolonged therapy is associated with significant side effects, and in refractory cases, immunomodulatory therapy is needed. We report a case of pyoderma gangrenosum, which developed in a 41-years-old woman, who showed no symptoms of having an underlying systemic disease. The conduction was successfully treated with prednisolone, cyclosporine and dapsone.
