A Case of Multiple Fungal Abscesses on Inguinal Area Caused by Itraconazole-resistant Trichophyton rubrum.
- Author:
Hyun Ji KANG
1
;
Chong Hyun WON
;
Sung Eun CHANG
;
Mi Woo LEE
;
Jee Ho CHOI
;
Woo Jin LEE
Author Information
1. Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. uucm79@gmail.com
- Publication Type:Case Report
- Keywords:
Fungal abscess;
Itraconazole;
Trichophyton rubrum;
Voriconazole
- MeSH:
Abscess*;
Amylases;
Arthrodermataceae;
Biopsy;
Drainage;
Hair;
Humans;
Hyphae;
Immunocompromised Host;
Itraconazole;
Methods;
Middle Aged;
Tinea;
Trichophyton*;
Voriconazole
- From:Korean Journal of Dermatology
2017;55(6):360-363
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dermatophytes usually infect keratinized epithelial structures such as hair and nails. However, they can also cause deep and extensive fungal infections, especially in immunocompromised patients. We report a case with multiple dermal abscesses, which is a rare manifestation of Trichophyton rubrum infection. A 54-year-old man presented with multiple subcutaneous nodules in both inguinal areas with associated tinea cruris. Histopathological findings showed abscesses with fungal hyphae highlighted using Periodic acid-Schiff diastase (PAS-D) staining. Trichophyton rubrum was isolated on a fungal culture of the biopsy specimen obtained from a subcutaneous nodule in the inguinal area. The lesions were resistant to treatment with itraconazole (100 mg twice a day for 6 months); thus, we changed the drug to voriconazole (200 mg twice a day for 3 months). In addition, we extracted the remaining big lesions by incision and drainage. The patient was successfully treated with voriconazole and surgical method.
