Mupirocin Ointment Prevents Early Post-Tympanostomy Tube Otorrhea: A Preliminary Study.
10.7874/kja.2012.16.3.130
- Author:
Kye Hoon PARK
1
;
Chi Kyou LEE
Author Information
1. Department of Otorhinolaryngology-Head & Neck Surgery, Soonchunhyang University School of Medicine, Cheonan, Korea. drqlee@hanmail.net
- Publication Type:Original Article
- Keywords:
Mupirocin;
Otorrhea;
Tube insertion;
Tympanostomy
- MeSH:
Anti-Bacterial Agents;
Calcium;
Child;
Drainage;
Ear;
Humans;
Middle Ear Ventilation;
Mupirocin;
Otitis Media;
Otitis Media with Effusion
- From:Korean Journal of Audiology
2012;16(3):130-133
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The most common complication of tympanostomy tube (T-tube) insertion is the development of postoperative otorrhea. Post-tympanostomy tube otorrhea (PTTO) is defined as active drainage through an existing T-tube. Many surgeons routinely use topical antibiotics as prophylaxis against early PTTO. Mupirocin calcium ointment is a topical antimicrobial agent with broad-spectrum antimicrobial activity against many Gram-positive organisms. This study evaluated the clinical effectiveness of topical mupirocin ointment in reducing early PTTO. SUBJECTS AND METHODS: The study included 98 ears (67 patients, mean age 32.9 years) that had a T-tube inserted because of chronic middle ear effusion or atelectatic otitis media. A Paparella type-I polyethylene-tube coated with mupirocin was inserted through the tympanostomy. Patients were instructed not to use otic drops or any other medications. All patients were seen by day 14 postoperatively. RESULTS: Early PTTO occurred in one case (1.5%). No early PTTO was seen with a middle ear effusion. Nineteen children were treated under general anesthesia; none developed early PTTO. CONCLUSIONS: Insertion of a T-tube coated with mupirocin ointment could be effective at preventing early PTTO.
