A Case of Unknown Primary Malignant Melanoma with Pulmonary and Endobronchial Metastasis.
10.4046/trd.2002.53.2.196
- Author:
Young Hoon MIN
1
;
Sung Wook KIM
;
Hui Jong CHIN
;
Tae Yoo LEE
;
Hun Ho SONG
;
Keun Seok LEE
;
Jung Ae LEE
;
Young Lee PARK
;
In Gyu HYUN
Author Information
1. Department of Internal Medicine, College of Medicine, Hallym University, Chunchon, Korea. youngiee@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Malignant melanoma;
Endobronchial metastasis
- MeSH:
Biopsy;
Neoplasm Metastasis
- From:Tuberculosis and Respiratory Diseases
2002;53(2):196-201
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Malignant melanoma is a highly malignant form of cutaneous cancer derived from melanocytes. The lesion frequently metastasizes to the lymph nodes, lung, liver and bone. However, an endobronchial metastasis and a primary malignant melanoma of the lung are quite rare. We report a case of an unknown primary malignant melanoma with a pulmonary and endobronchial metastasis in a 34 years old male. He complained of coughing and black-colored sputum. Abnormal skin and mucosal lesions were not found during a physical examination. A chest X-ray revealed multiple nodular masses in both lung fields. A flexible bronchoscopy showed two yellowish small nodules at the entry of left lower bronchus. Vimentin, the S-100 protein, and HMB-45 stain positive melanoma cells were detected at the bronchoscopic biopsy specimen.