Experience with reversal of a neuromuscular block with sugammadex in a child with Prader-Willi syndrome: A case report.
10.17085/apm.2017.12.4.335
- Author:
Tae Yun SUNG
1
;
Taehoon KANG
;
Choon kyu CHO
;
Hee Uk KWON
;
Po Soon KANG
;
Young Seok JEE
Author Information
1. Department of Anesthesiology and Pain Medicine, Konyang University College of Medicine, Daejeon, Korea. jisaac@naver.com
- Publication Type:Case Report
- Keywords:
Hypotonia;
Prader-Willi syndrome;
Pulmonary hypertension;
Remifentanil;
Rocuronium;
Sugammadex
- MeSH:
Airway Obstruction;
Anesthesia;
Child*;
Child, Preschool;
Humans;
Hypertension, Pulmonary;
Inhalation;
Muscle Hypotonia;
Neuromuscular Blockade*;
Neuromuscular Monitoring;
Prader-Willi Syndrome*
- From:Anesthesia and Pain Medicine
2017;12(4):335-338
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We treated a 4-year-old patient with a genetic disorder, Prader-Willi syndrome, that was accompanied by pulmonary hypertension due to upper airway obstruction. Prader-Willi syndrome is a complex genetic condition characterized by hypotonia, feeding difficulties, poor growth, and delayed development. Hypotonia was the main concern in the anesthetic management of this patient, including the choice of a neuromuscular blocking agent. We report successful induction of anesthesia in this patient with sevoflurane inhalation, remifentanil infusion, and a non-depolarizing muscle relaxant, rocuronium, while following up the status of the neuromuscular block by train-of-four monitoring and reversing the neuromuscular block with sugammadex.
