Polycan-calcium gluconate complex improves gingival health.
10.11149/jkaoh.2013.37.4.175
- Author:
Youn Hee CHOI
1
;
Ji Hye KIM
;
Jae Young KIM
;
Young Kyun LEE
;
Hae Young YANG
;
Keun Bae SONG
Author Information
1. Department of Preventive Dentistry, Kyungpook National University School of Dentistry, Daegu, Korea. kbsong@knu.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
beta-glucan;
Calcium gluconate;
Gingival health;
Polycan
- MeSH:
Biomarkers;
Calcium Gluconate;
Diagnosis, Oral;
Enzyme-Linked Immunosorbent Assay;
Gingival Crevicular Fluid;
Interleukins;
Mouth;
Periodontitis
- From:Journal of Korean Academy of Oral Health
2013;37(4):175-179
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVES: The aim of this study was to examine the effect of a Polycan-calcium gluconate complex on gingival health. METHODS: Forty-one subjects with mild periodontitis (> or =40 years) were divided into two groups: the placebo and test product (Polycan-calcium gluconate complex twice a day for 4 weeks) groups. Oral examination was performed and gingival crevicular fluid (GCF) was collected from each subject at baseline and after 4 weeks. Interleukin (IL)-1beta level in the GCF was determined using enzyme-linked immunosorbent assay. RESULTS: Pocket depth and plaque index were significantly decreased in the test group at 4 weeks. The level of IL-1beta and plaque index of the treatment group was significantly lower than of the placebo group. CONCLUSIONS: Based on the above results, Polycan-calcium gluconate complex may inhibit plaque accumulation in the mouth and may have a negative correlation with the level of inflammatory biomarkers. Consequently, gingival health was significantly improved by polycan-calcium gluconate complex.
