Influence of Intravitreal Bevacizumab Injection on Formation of Collateral Vessels in Branch Retinal Vein Occlusion.
10.3341/jkos.2016.57.4.582
- Author:
Yeng Woo SON
1
;
Seung Woo LEE
Author Information
1. Department of Ophthalmology, Dongguk University College of Medicine, Gyeongju, Korea. jazzhanul@hanmail.net
- Publication Type:Original Article
- Keywords:
Bevacizumab;
Collateral Vessels;
Macular Edema;
Retinal Vein Occlusion
- MeSH:
Diagnosis;
Humans;
Incidence;
Macular Edema;
Medical Records;
Retinal Vein Occlusion*;
Retinal Vein*;
Retinaldehyde*;
Bevacizumab
- From:Journal of the Korean Ophthalmological Society
2016;57(4):582-587
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the influence of retinal collateral vessels in eyes with macular edema secondary to branch retinal vein occlusion (BRVO) treated with intravitreal bevacizumab (IVB). METHODS: We reviewed the medical records of patients with BRVO who were followed up for 12 months. To compare formations of collateral vessels, the patients were divided into 2 groups. The treatment group included 20 patients (20 eyes) treated with IVB, and the control group included 41 patients (41 eyes) without treatment. RESULTS: In the treatment group, the mean age was 58.4 ± 9.5 years. The average number of IVB injections performed during the 12 months was 4.5 ± 2.5 (range 2 to 8). After 12 months from diagnosis, 13 eyes (65%) presented with collateral vessels. In the control group, the mean age was 60.6 ± 9.3 years and 28 eyes (68.3%) presented with collateral vessel after 12 months. There was no difference in incidence of collateral vessel formation between the treatment group and the control group (p = 0.574). CONCLUSIONS: IVB does not influence the formation of retinal collateralization in eyes treated for macular edema secondary to BRVO.