A Case of Cutaneous Alternariosis.
- Author:
Jung Hun KO
1
;
Sung Han KIM
;
Kyu Chul CHOI
;
Byoung Soo CHUNG
Author Information
1. Department of Dermatology, Chosun University Medical School, Kwangju, Korea. bsjung@chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous alternariosis;
Alternaria species
- MeSH:
Alternaria;
Alternariosis*;
Biopsy;
Cushing Syndrome;
Dermis;
Epithelioid Cells;
Female;
Forearm;
Fungi;
Humans;
Hyphae;
Immunocompromised Host;
Lymphocytes;
Middle Aged;
Neutrophils;
Opportunistic Infections;
Plants;
Plasma Cells;
Recurrence;
Spores;
Ulcer
- From:Korean Journal of Medical Mycology
2002;7(3):165-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Alternaria species are common plant pathogens and saprophytic fungi. Cutaneous alternariosis is rare and an opportunistic infection in both healthy and immunosuppressed hosts. We report a case of cutaneous alternariosis developed in a 60-year-old female with iatrogenic Cushing syndrome. She had several various sized confluent suppurative ulcers on erythematous plaques on the both forearm clinically. Histology showed mixed-cell granulomatous infiltration with epithelioid cells, lymphocytes, neutrophils and a few plasma cells in the dermis. Many branching septate hyphae and spores were noted within the granulomatous tissue stained with PAS. A fungal culture from biopsy specimen revealed Alternaria species; pigmented hyphae and cornidia which had both transverse and longitudinal septae. The cutaneous lesions treated with terbinafine, 250 mg daily, for 3 months and 1 year later there is no evidence of recurrence.
