A Case of Conjunctival Mass with Infectious Mononucleosis by EBV.
10.3341/jkos.2014.55.10.1554
- Author:
Kyoung Yoon SHIN
1
;
Moo Hwan CHANG
;
Sung Eun KYUNG
Author Information
1. Department of Ophthalmology, Dankook University Medical College, Cheonan, Korea. kseeye@hanmail.net
- Publication Type:Case Report
- Keywords:
Conjunctival mass;
Infectious mononucleosis
- MeSH:
Biopsy;
Capsid;
Conjunctiva;
Diagnosis, Differential;
Fever;
Herpesvirus 4, Human*;
Humans;
Immunoglobulin M;
In Situ Hybridization;
Infectious Mononucleosis*;
Inflammation;
Leukocyte Count;
Lymphocytes;
Male;
Palatine Tonsil;
Pediatrics;
Pharyngitis;
Polymerase Chain Reaction
- From:Journal of the Korean Ophthalmological Society
2014;55(10):1554-1557
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report a case of conjunctival mass with infectious mononucleosis by Epstein-Barr virus (EBV) confirmed with Epstein-Barr encoding region (EBER) in situ hybridization. CASE SUMMARY: A 8 year-old male without underlying disease was referred with counjunctival mass on the right eye starting 3 days ago. In ophthalmologic evaluation, there was injected, nontender, and "salmon patch" appearance conjunctival lesion on right superior bulbar conjunctiva. The patient was admitted to pediatrics with sore throat and fever. The tonsil were enlarged and white blood cell count was 14960/uL. EBV polymerase chain reaction (PCR) test and Viral capsid antigen Immunoglobulin M (VAC IgM) test were positive, the diagnose of infectious mononucleosis by EBV was made. After 5 days steroid eyedrop therapy, biopsy was performed because the lesion was not improved. There were lymphocyte infiltration, chronic inflammation and positive in EBER in situ hybridization. CONCLUSIONS: Elevated and pinkish lesion on conjunctiva, EBV lesion should be considered as differential diagnosis.
