A Case of Cerebral Malaria Associated with Renal Failure due to Plasmodium falciparum.
- Author:
Moon Soo KANG
1
;
Jong Weon CHOI
;
Chung Hyun NAHM
;
Soo Hwan PAI
Author Information
1. Department of Clinical Pathology, Inha University College of Medicine, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Cerebral malaria;
Renal failure;
Plasmodium falciparum
- MeSH:
Acute Kidney Injury;
Coma;
Disseminated Intravascular Coagulation;
Drug Therapy;
Humans;
Incidence;
Indonesia;
Korea;
Laos;
Malaria, Cerebral*;
Male;
Mortality;
Plasmodium falciparum*;
Plasmodium*;
Renal Dialysis;
Renal Insufficiency*;
Respiration;
Trophozoites
- From:Korean Journal of Clinical Pathology
2000;20(5):459-462
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In recent years, the incidence of imported cases infested with Plasmodium falciparum has been increasing in Korea due to marked increase in travel to malarious area without adequate prophylaxis. Cerebral malaria is an encephalopathy, occasionally associated with infestation of P. falciparum, which can complicate some patients infected with Plasmodium falciparum leading to significant mortality. We experienced a case of 45 year-ld male with cerebral malaria, complicated with disseminated intravascular coagulation and acute renal failure. The patient was thought to be infected in travel to Indonesia, Laos, and Bangkok. Blood smear showed typical multiple intra-rythrocytic ring form trophozoites and banana-haped gametocytes of Plasmodium falciparum. The patient died after comatose state with respiration failure for 24 days despite treatment with exchange transfusion, hemodialysis and chemotherapy. We report this case with a review of the literature.