Acute Retrobulbar Optic Neuritis with Hematologic Abnormalities.
10.3341/jkos.2014.55.10.1567
- Author:
Si Yoon PARK
1
;
Eun Min KANG
;
Yun Ha LEE
;
Chan Yun KIM
;
Gong Je SEONG
;
Samin HONG
Author Information
1. Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea. samini@yuhs.ac
- Publication Type:Case Report
- Keywords:
Autoimmune disease;
Idiopathic thrombocytopenic purpura;
Multiple sclerosis;
Neuromyelitis optica;
Optic neuritis
- MeSH:
Adult;
Antibodies;
Autoimmune Diseases;
Brain;
Erythrocytes;
Female;
Hematocrit;
Humans;
Lymphocytes;
Lymphocytosis;
Magnetic Resonance Imaging;
Multiple Sclerosis;
Neuromyelitis Optica;
Optic Neuritis*;
Papilledema;
Platelet Count;
Prednisolone;
Pupil Disorders;
Purpura, Thrombocytopenic, Idiopathic;
Visual Acuity;
Visual Fields
- From:Journal of the Korean Ophthalmological Society
2014;55(10):1567-1572
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We present a case of a patient with optic neuritis who had underlying suspicious idiopathic thrombocytopenic purpura. CASE SUMMARY: 35-year-old female with no other systemic disease visited our clinic due to acutely decreased visual acuity in her left eye 10 days in duration. Relative afferent pupillary defect was observed, but without definite papilledema. Based on brain magnetic resonance imaging (MRI), optic neuritis was suspected. Laboratory tests showed increased red blood cells, hemoglobin and, hematocrit levels and decreased platelets. Peripheral blood smear test showed decreased platelets, relative lymphocytosis and atypical lymphocytes. Specific antibodies for autoimmune disease were not present. High-dose steroid pulse therapy (methyl prednisolone 1.0 g/d, 3 days) was started. One month after treatment her visual acuity and platelet count recovered and her visual field defect improved.
