Risk Factors Associated with Germinal Matrix-Intraventricular Hemorrhage in Preterm Neonates.
10.3340/jkns.2014.56.4.334
- Author:
Kwang Ryeol KIM
1
;
Sang Won JUNG
;
Dong Won KIM
Author Information
1. Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine, Daegu, Korea. dongwonkim@dsmc.or.kr
- Publication Type:Original Article
- Keywords:
Germinal matrix-intraventricular hemorrhage;
Gestational age;
Ductus arteriosus, patent
- MeSH:
Birth Weight;
Ductus Arteriosus, Patent;
Gestational Age;
Glucose;
Hemorrhage*;
Humans;
Infant, Newborn*;
Intensive Care, Neonatal;
Logistic Models;
Membranes;
Precipitating Factors;
Risk Factors*;
Rupture;
Sodium;
Ultrasonography
- From:Journal of Korean Neurosurgical Society
2014;56(4):334-337
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The purpose of this study is to identify the risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) and the relationship of the severity of disease and prematurity. METHODS: A total of 168 premature neonates whose birth weight < or =1500 g or gestational age < or =34 weeks were examined by cranial ultrasound (CUS) for detection of GM-IVH among the babies admitted between January 2011 and December 2012 in our medical center neonatal intensive care unit. The babies were divided into two groups : GM-IVH and non-IVH. Clinical presentations, precipitating factors of the patients and maternal factors were analyzed. RESULTS: In univariate analysis, gestational age, birth weight, delivery method, presence of premature rupture of membrane (PROM) and level of sodium and glucose were statistically meaningful factors (p<0.05). But only two factors, gestational age and presence of patent ductus arteriosus (PDA) were statistically meaningful in multivariate logistic regression (p<0.05). Delivery method [normal vaginal delivery (NVD) to Caeserean section] was borderline significant (p<0.10). CONCLUSION: Presence of PDA and gestational age were the important risk factors associated with development of GM-IVH.
