Weight Gain in Pregnancy, Maternal Age and Gestational Age in Relation to Fetal Macrosomia.
- Author:
Yi LI
1
;
Qi Fei LIU
;
Dan ZHANG
;
Ying SHEN
;
Kui YE
;
Han Lin LAI
;
Hai Qing WANG
;
Chuan Lai HU
;
Qi Hong ZHAO
;
Li LI
Author Information
- Publication Type:Original Article
- Keywords: Body mass index; Fetal macrosomia; Pregnancy; Risk factors
- MeSH: Body Mass Index; Child; Child Care; Cohort Studies; Female; Fetal Macrosomia*; Gestational Age*; Humans; Incidence; Infant, Newborn; Logistic Models; Male; Maternal Age*; Medical Records; Parity; Pregnancy*; Pregnant Women; Prospective Studies; Retrospective Studies; Risk Factors; Weight Gain*; Surveys and Questionnaires
- From:Clinical Nutrition Research 2015;4(2):104-109
- CountryRepublic of Korea
- Language:English
- Abstract: To investigate the possible risk factors related to macrosomia. Pregnant women and their newborns (n = 1041) were recruited from a cohort study in Maternal and Child Care Center of Hefei from January 2011 to July 2012. Questionnaires were applied to collect the demographic data besides the medical records. Detailed health records of the entire pregnancy were obtained using retrospective study. Meanwhile the data of neonatal outcomes was prospectively tracked. Associations between exposure risk factors and macrosomia were analyzed using Pearson's chi squared test. Logistic regression models were used to assess the independent association between these potential predictors and macrosomia. The incidence of macrosomia of this cohort was 11.24% of which male: female = 2.55:1. Male incidence (8.07%)of macrosomia was higher than female (3.17%), p < 0.001. Body mass index (BMI) before pregnancy (pre-BMI), maternal height, parity were not independently associated with macrosomia; Multiple logistic regression analysis indicated that macrosomia was mainly independently associated with weight gain in pregnancy (OR=1.14, 95% CI [1.10-1.19]), maternal age (OR = 1.09, 95% CI [1.03-1.15]) and gestational age (OR = 1.62, 95% CI [1.31-1.99]), respectively. Our findings indicate that weight gain in pregnancy, maternal age and gestational age should be considered as independent risk factors for macrosomia.
