Clinical Impact of High Triglycerides and Central Obesity in Patients with Acute Myocardial Infarction who Underwent Percutaneous Coronary Intervention.
- Author:
Soo Gyoung HAN
1
;
Myung Ho JEONG
;
Jung Ae RHEE
;
Jin Su CHOI
;
Kee Hong LEE
;
Keun Ho PARK
;
Doo Sun SIM
;
Young Joon HONG
;
Ju Han KIM
;
Young Keun AHN
;
Jeong Gwan CHO
;
Jong Chun PARK
;
Jung Chaee KANG
Author Information
1. The Heart Center of Chonnam National University Hospital, Gwangju, Korea. myungho@chollian.net
- Publication Type:Original Article
- Keywords:
Acute myocardial infarction;
Obesity;
Triglyceride;
Mortality
- MeSH:
Dyslipidemias;
Follow-Up Studies;
Hospital Mortality;
Humans;
Mortality;
Myocardial Infarction*;
Obesity;
Obesity, Abdominal*;
Percutaneous Coronary Intervention*;
Risk Factors;
Triglycerides*
- From:Korean Journal of Medicine
2014;86(2):169-178
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Dyslipidemia and obesity are risk factors for the development of acute myocardial infarction (AMI) that affect the clinical outcomes in patients. METHODS: We analyzed 2,751 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) (mean age, 63.7 +/- 12.1 years). The patients were divided into four groups based on serum triglyceride levels and central obesity [Group Ia: triglycerides < 200 mg/dL and (-) central obesity; Group Ib: triglyceride < 200 mg/dL and (+) central obesity; Group IIa: triglyceride > or = 200 mg/dL and (-) central obesity; Group IIb: triglyceride > or = 200 mg/dL and (+) central obesity]. In-hospital outcome was defined as in-hospital mortality and complications. One-year clinical outcome was compared and defined as the composite of 1-year major adverse cardiac events (MACE), including death, recurrent MI, and target vessel revascularization. RESULTS: Total MACE developed in 502 patients (18.2%), while 303 patients (11.0%) died prior to the 1-year follow-up visit. In-hospital complications and in-hospital mortality were not different among the four groups. One-year clinical outcomes based on triglyceride levels (Group I vs. Group II) were not different. In addition, there were no differences in clinical outcomes in patients with a triglyceride level < 200 mg/dL, regardless of central obesity. One-year MACE rates were not significantly different among the four groups. CONCLUSIONS: There was no significant difference in the 1-year MACE rate based on the triglyceride level and presence of central obesity in patients with AMI who underwent PCI.
