Difficult diagnosis and localization of focal nesidioblastosis: clinical implications of ⁶⁸Gallium-DOTA-D-Phe¹-Tyr³-octreotide PET scanning.
10.4174/astr.2016.91.1.51
- Author:
Jae Ri KIM
1
;
Jin Young JANG
;
Yong Chan SHIN
;
Young Min CHO
;
Hongbeom KIM
;
Wooil KWON
;
Young Min HAN
;
Sun Whe KIM
Author Information
1. Department of Surgery and Cancer Research Institute, Seoul National University College of Medicine, Seoul, Korea. jangjy4@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Nesidioblastosis;
Ga(III)-DOTATOC;
Positron-emission tomography
- MeSH:
Adult;
Diagnosis*;
Female;
Humans;
Hyperplasia;
Hypoglycemia;
Islets of Langerhans;
Middle Aged;
Nesidioblastosis*;
Octreotide;
Positron-Emission Tomography*;
Surgeons
- From:Annals of Surgical Treatment and Research
2016;91(1):51-55
- CountryRepublic of Korea
- Language:English
-
Abstract:
Focal nesidioblastosis is a rare cause of endogenous hyperinsulinemic hypoglycemia in adults. Because it is difficult to localize and detect with current imaging modalities, nesidioblastosis is challenging for biliary-pancreatic surgeons. ⁶⁸Gallium-DOTA-D-Phe¹-Tyr³-octreotide PET scanning and ¹¹¹indium-pentetreotide diethylene triamine pentaacetic acid octreotide scanning may be superior to conventional imaging modalities in determining the localization of nesidioblastosis. We report the successful surgical treatment of a 54-year-old woman with focal hyperplasia of the islets of Langerhans, who experienced frequent hypoglycemic symptoms and underwent various diagnostic examinations with different results.
