Transcatheter arterial chemoembolization of hepatocellular carcinoma with portal vein invasion.
10.3348/jkrs.1993.29.4.698
- Author:
Young Rahn LEE
;
Ki Yeol LEE
;
Seong Beom CHO
;
In Ho CHA
;
Kyoo Byung CHUNG
- Publication Type:Original Article
- MeSH:
Carcinoma, Hepatocellular*;
Drug Therapy;
Humans;
Methods;
Portal Vein*;
Prognosis;
Thrombosis
- From:Journal of the Korean Radiological Society
1993;29(4):698-703
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Transcatheter arterial chemoembolization(TACE) is an imperative method for the managment of inoperable hepatocellular carcinoma(HCC). It is well known that primary HCC frequently invades the portal venous system and forms a tumor thrombus obstructing the portal blood flow which makes unfavorable prognosis of patiebt. We retrospetively reviewed 58 patients who reveived TACE(minimum 3 times) of HCC invading into portal venous system. Group 1(n=29) which showed peripheral portal vein invasion had better clinical and laboratory response. Group 2(n=17) which showed first order portal branch invasion had similar response to Group 3(n=12), which had main portal invasion. Group 1 showed no difference in survival time between TAC and TACE, but, in Group 2 and 3, emboliation with chemotherapy made longer survival than chemotherapy only. Clinical level of AFP was meaningful in Group 1 and 2 as decreasing value. Our results provides that careful selection of TACE and case by case Coil/Gelfoam embolization can improve the mean survival and clinical response when HCC evidently invades portal venous system.
