Lipid Profile Changes in Infection of Plasmodium Vivax.
- Author:
Chul SIN
1
;
Dong Joon LIM
;
Tae Jin SONG
;
Kyu Chul LEE
;
Inbum SUH
;
Soo Young YOON
;
Chae Seung LIM
Author Information
1. Division of Respiratory Disease, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Plasmodium vivax;
Malaria;
Lipid profile;
Total cholesterol;
Triglycerides;
HDL cholesterol;
LDL cholesterol
- MeSH:
Cholesterol;
Cholesterol, HDL;
Cholesterol, LDL;
Diagnosis;
Humans;
Malaria;
Malaria, Vivax;
Parasitemia;
Plasma;
Plasmodium vivax*;
Plasmodium*;
Platelet Count;
Triglycerides
- From:Korean Journal of Infectious Diseases
2001;33(1):58-61
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Alteration in plasma lipid levels during malaria attacks was studied to evaluate the diagnstic values in vivax malaria. METHODS: The plasma levels of total cholesterol, triglycerides, HDL-cholesterol (HDL-c), and LDL-cholesterol (LDL-c) were analyzed and compared in 32 patients with vivax malaria at presentation, in 10 patients after 17-days of treatment with anti-malaria drug, and in 40 control individuals. Interrelation of lipid profile with other parameters including parasitemia level, platelet count, hemoglobin and WBC counts were analysed. RESULTS: In patients with malaria, serum total cholesterol, triglycerides, HDL-c and LDL-c concentrations were significantly lower than those of control subjects. None of lipid profile showed any correlation with the parasitemia level. After treatment, HDL-c was significantly elevated. CONCLUSION: These results suggest that lipid profile, especially decreased of HDL-c, may be a valuable information in the diagnosis of the malaria.
