Diagnosis of Helicobacter pylori Infection by Pronto Dry Test.
- Author:
Su Jin HONG
1
;
Chang Beom RYU
;
In Sup JUNG
;
Jin Oh KIM
;
Joo Young CHO
;
Joon Seong LEE
;
Moon Sung LEE
;
So Young JIN
;
Chan Sup SHIM
Author Information
1. Department of Internal Medicine, Soon Chun Hyang University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Pronto Dry test;
Rapid urease test;
Helicobacter pylori
- MeSH:
Biopsy;
Breath Tests;
Diagnosis*;
Gastroscopy;
Helicobacter pylori*;
Helicobacter*;
Humans;
Polymerase Chain Reaction;
Reaction Time;
Sensitivity and Specificity;
Urea;
Urease
- From:Korean Journal of Gastrointestinal Endoscopy
2001;22(2):70-75
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Pronto Dry test, a new rapid urease test, is consisted of a dry filter paper containing urea and has been reported to have a more rapid reaction time than others. We performed this study to compare the accuracy of Pronto Dry test with the other conventional tests for detection of H. pylori. METHODS: One hundred patients underwent gastroscopy in our hospital for gastrointestinal symptoms. Biopsy specimens were taken for Pronto Dry test, polymerase chain reaction, culture, and histologic examination (Warthin-Starry stain). 13C-urea breath test was also performed. The results of Pronto Dry test were read after 1 hour. RESULTS: The sensitivity, specificity, positive and negative predictive value of Pronto Dry test to diagnose H. pylori infection were 90.0%, 100%, 100%, and 90.9%, respectively. The kappa statistic between H. pylori status and Pronto Dry test was 0.90, demonstrating an acceptable level of reliability. CONCLUSIONS: Pronto Dry test has a high sensitivity and specificity, and can be used as a rapid test to diagnose H. pylori infection.
