Removal by Mohs Micrographic Surgery and Reconstruction Using Combined Local Flaps.
- Author:
Jooyoung KIM
1
;
Kee Yang CHUNG
Author Information
1. Department of Dermatology, Yonsei University College of Medicine, Seoul, Korea. kychung@yumc.yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Xeroderma pigmentosum;
Mohs micrographic surgery;
Basal cell carcinoma;
Dorsal nasal flap;
Cheek advancement flap;
Full thickness skin graft
- MeSH:
Aged;
Carcinoma, Basal Cell;
Cheek;
DNA Damage;
Female;
Humans;
Melanosis;
Mohs Surgery*;
Phenotype;
Photophobia;
Skin;
Skin Diseases;
Transplants;
Wills;
Xeroderma Pigmentosum
- From:Korean Journal of Dermatology
2003;41(10):1354-1358
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Xeroderma pigmentosum is a group of dermatoses characterized by autosomal recessive inheritance, photosensitivity, photophobia, early onset freckles, and subsequent cutaneous neoplastic changes on sun-exposed areas. It is due to enzymatic defects that render the cells unable to repair UV-induced DNA damages resulting in various clinical phenotypes. A 66-year-old female patient who has been diagnosed as xeroderma pigmentosum twenty years ago developed a recurrent basal cell carcinoma on the right nasal side-wall, resulting in a large defect that comprises multiple aesthetic units, after a Mohs micrographic surgery. A combination of dorsal nasal and cheek advancement flaps with full thickness skin graft was a useful method for the reconstruction of the large nasal defect.
