Two Cases of Gastric MALT Lymphoma Diagnosed at Long Last after Successful Eradication of Helicobacter pylori.
10.7704/kjhugr.2012.12.4.265
- Author:
Soo Jeong YEOM
1
;
In Seok LEE
;
Seok Goo CHO
;
Myung Gyu CHOI
;
Kyu Yong CHOI
;
Gyeong Sin PARK
Author Information
1. Department of Internal Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea. isle@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Helicobacter pylori;
MALT lymphoma;
Eradication
- MeSH:
Cell Proliferation;
Colon;
Epithelium;
Gastric Mucosa;
Helicobacter;
Helicobacter pylori;
Humans;
Lymphoid Tissue;
Lymphoma, B-Cell, Marginal Zone;
Rare Diseases
- From:The Korean Journal of Helicobacter and Upper Gastrointestinal Research
2012;12(4):265-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The gastric marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) is a rare disease. Helicobacter pylori infection is known as an important etiologic factor of the pathogenesis of MALT lymphoma. H. pylori colonization at the epithelium of gastric mucosa induces T cell and B cell recruitment. T cell induced B cell proliferation develops the MALT in the gastric mucosa. Monoclonal proliferation of B cell in the MALT transform into MALT lymphoma. The eradication of H. pylori is known to induce remission of the disease in more than 80% of patients. But there is no report on progression and development of MALT lymphoma after H. pylori eradication. We experienced two cases of gastric B cell MALT lymphoma diagnosed at long last, after the successful eradication of H. pylori.
