Ocular Sarcoidosis in a Korean Population.
10.3346/jkms.2009.24.3.413
- Author:
Sun Young LEE
1
;
Hee Gyung LEE
;
Dong Soon KIM
;
June Gone KIM
;
Hyewon CHUNG
;
Young Hee YOON
Author Information
1. Department of Ophthalmology, Asan Medical Center, College of Medicine, University of Ulsan, Seoul, Korea. yhyoon@amc.seoul.kr
- Publication Type:Original Article
- Keywords:
Korean;
Ocular Sarcoidosis;
Sarcoidosis;
Uveitis
- MeSH:
Adult;
Age Factors;
Asian Continental Ancestry Group;
Choroiditis/diagnosis;
Eye Diseases/*diagnosis/epidemiology/therapy;
Female;
Fluorescein Angiography;
Humans;
Male;
Middle Aged;
Retinal Vasculitis/diagnosis;
Retrospective Studies;
Sarcoidosis/*diagnosis/epidemiology/therapy;
Steroids/therapeutic use;
Uveitis, Anterior/diagnosis;
Uveitis, Intermediate/diagnosis
- From:Journal of Korean Medical Science
2009;24(3):413-419
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of current study was to evaluate the incidence and characteristics of ocular sarcoidosis in a Korean population. We conducted a retrospective study of 104 consecutive patients with biopsy-proven sarcoidosis seen at Asan Medical Center in Seoul, Korea, from 1993 to 2007. Medical records, photographs, and fluorescein angiograms were reviewed. Of 104 patients, 22 (21%) had intraocular involvement with female predominance (86%, M:F=3:19). Of the 39 eyes with ocular involvement, 16 (41%) eyes had isolated anterior uveitis, 12 (31%) eyes had intermediate uveitis, 6 eyes (15%) had panuveitis with retinal vasculitis, and 5 (13%) eyes had panuveitis with punched multifocal choroiditis. Mean duration of ophthalmologic follow-up was 62 months. All ocular inflammation was well managed with topical steroid and/or systemic steroid with relatively good final visual outcomes. Ocular complications such as cataract (12 eyes, 30%), glaucoma (6 eyes, 15%), vitreous opacity (1 eye, 3%), cystoid macular edema (3 eyes, 7%), neovascularization (2 eye, 5%), and epiretinal membrane (4 eye, 10%) were related to ocular sarcoidosis. In Korea, where sarcoidosis is very rare, our study indicates relatively low ocular and predominantly non posterior segment involvement with relatively good visual prognosis.
