Comparison of Clinical and Radiographic Characteristics between Nodular Bronchiectatic Form of Nontuberculous Mycobacterial Lung Disease and Diffuse Panbronchiolitis.
10.3346/jkms.2009.24.3.427
- Author:
Hye Yun PARK
1
;
Gee Young SUH
;
Man Pyo CHUNG
;
Hojoong KIM
;
O Jung KWON
;
Myung Jin CHUNG
;
Tae Sung KIM
;
Kyung Soo LEE
;
Won Jung KOH
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. wjkoh@skku.edu
- Publication Type:Original Article ; Comparative Study ; Research Support, Non-U.S. Gov't
- Keywords:
Nontuberculous Mycobacteria;
Bronchiectasis;
Bronchiolitis;
Mycobacterium Avium Complex
- MeSH:
Adult;
Age Factors;
Aged;
Bronchiectasis/*diagnosis/radiography;
Bronchiolitis/*diagnosis/radiography;
Diagnosis, Differential;
Female;
Humans;
Lung Diseases/*diagnosis/microbiology/radiography;
Male;
Middle Aged;
Mycobacterium Infections/*diagnosis/radiography;
Mycobacterium avium Complex;
Mycobacterium avium-intracellulare Infection/diagnosis/radiography;
Respiratory Function Tests;
Sex Factors;
Tomography, X-Ray Computed;
Tuberculosis, Pulmonary/therapy
- From:Journal of Korean Medical Science
2009;24(3):427-432
- CountryRepublic of Korea
- Language:English
-
Abstract:
The nodular bronchiectatic form of nontuberculous mycobacterial (NTM) lung disease and diffuse panbronchiolits (DPB) show similar clinical and radiographic findings. The present study was performed to clarify the clinicoradiographic similarities as well as the differences between NTM lung disease and DPB. The initial clinicoradiographic features of 78 patients with the nodular bronchiectatic form of NTM lung disease (41 patients with Mycobacterium avium complex infection and 37 patients with Mycobacterium abscessus infection) were compared with those of 35 patients with DPB. Old age, female sex, a history of tuberculosis treatment, and hemoptysis were related to NTM lung disease while exertional dyspnea, coarse crackles, history of sinusitis, obstructive abnormalities in pulmonary function tests, and hypoxemia were related to DPB. The number of lobes involved with bronchiolitis and bronchiectasis on chest computed tomography were more numerous in DPB patients. There is considerable overlap in the clinical and radiographic appearances of the nodular bronchiectatic form of NTM lung disease and DPB, although some clinicoradiographic features differ between two diseases. The correct diagnosis, including aggressive microbiologic evaluation, should be made for the appropriate management of patients presenting with bilateral bronchiectasis and bronchiolitis.
