Clinical Manifestations of Ureteral Duplication in Children.
- Author:
Jung Woo HAN
1
;
Dae Hwan HWANG
;
Jee Min PARK
;
Jae Seung LEE
;
Sang Won HAN
Author Information
1. Department of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine, Seoul, Korea. jsyonse@yumc.yonsei.ac.kr
- Publication Type:Multicenter Study ; Original Article
- Keywords:
Ureteral duplication;
Prenatal sonography;
Antenatal care
- MeSH:
Child*;
Diagnosis;
Early Diagnosis;
Humans;
Korea;
Retrospective Studies;
Seoul;
Succimer;
Ultrasonography;
Ureter*
- From:Journal of the Korean Society of Pediatric Nephrology
2003;7(2):189-196
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Ureteral duplication is a common urologic anomaly and early diagnosis may prevent irreversible renal damage. We thus aimed to evaluate the benefits of prenatal sonography in early detection. METHODS: We retrospectively studied 55 children with duplicated systems who were admitted to Severance Hospital, Yonsei University, Seoul, Korea from January 1998 to July 2003. RESULTS: The mean age at diagnosis was 2.3 years old. 89% of the children had complete duplicated ureter. 47% of the children visited the hospital with an initial complaint of abnormal prenatal sonographic findings. Among these patients, 70.8% had DMSA defects. The mean differential renal function(DRF) in the DMSA scan was 48.2% in the group diagnosed prenatally. In the postnatally-diagnosed group, DMSA defects were found in 67.7% patients and the mean DRF was 45.5%. CONCLUSION: In comparison with the past studies, the mean age at diagnosis is becoming younger, and the proportion of abnormal prenatal sonography as an initial complaint larger. Other clinical manifestations were similar. The difference of the renal damage between the prenatally diagnosed group and the postnatally diagnosed group was not statistically significant. A multi-center study may help to prove the importance of prenatal sonography in early diagnosis and treatment of ureteral duplication.
