The Change of Multifocal Visual Evoked Potential in Unilateral Anisometropic Amblyopia before and after Occlusion Treatment.
10.3341/jkos.2012.53.12.1851
- Author:
Ji Hoon JEON
1
;
Sung Eun KYUNG
Author Information
1. Department of Ophthalmology, Dankook University College of Medcine, Cheonan, Korea. kseeye@hanmail.net
- Publication Type:Original Article
- Keywords:
Anisometropic amblyopia;
Multifocal visual evoked potential;
Occlusion treatment;
Ring 1
- MeSH:
Amblyopia;
Evoked Potentials, Visual;
Eye;
Humans;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2012;53(12):1851-1856
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the change in multifocal visual evoked potential (mfVEP) in unilateral anisometropic amblyopia before and after occlusion treatment. METHODS: The mfVEP was performed using RETIscan(R) (Roland,Brandenburg, Germany) for patients with unilateral anisometropic amblyopia before and after occlusion treatment. Amplitude and latency values of mfVEP were analyzed according to the field divided by 6 rings or 4 sectors. RESULTS: The each amplitude of values of all 6 rings were not significantly different before treatment (p = 0.077) in amblyopic eyes. However, the value of ring 1 (p = 0.00) was significantly higher than the value of other rings after treatment. In fellow eyes, the values of ring 1 was consistently significantly higher than the value of other rings before (p = 0.014) and after (p = 0.049) occlusion treatment. Additionally, the amplitudes of ring 1 (p = 0.005) and ring 3 (p = 0.007) were significantly increased in amblyopic eyes after occlusion treatment. In fellow eyes, the values of all rings did not change significantly. The analysis of amplitudes with 4 sectors revealed no significant result. The analysis of latencies with 6 rings and 4 sectors revealed no significant result. CONCLUSIONS: The change in amplitude on the central field (ring 1) in amblyopic eyes can be a useful objective monitoring method observing the improvement progress in visual acuity.