The extrapolation method in dosage is equivalent in effectiveness between man and experimental animals
- Author:
Dam Trung Do
- Publication Type:Journal Article
- Keywords:
extrapolation
- MeSH:
Dosage Forms;
Animal Experimentation
- From:Pharmaceutical Journal
1999;282(10):7-9
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Introduction on the factors influence dosage that is equivalent in effectiveness between animals. They comprised drug metabolism, minimum concentration have with effect in serum, the effective time, cellular respiration, organic weight rate comparison with body weight, heat production, cytochrom C, volume of kidney and body surface.