Dysarthria after Donepezil.
- Author:
San JUNG
1
;
Jong Sam BAIK
Author Information
1. Department of Neurology, Kyunggi Provincial Hospital For The Elderly.
- Publication Type:Original Article
- Keywords:
Alzheimer's disease;
Donepezil;
Dysarthria
- MeSH:
Acetylcholinesterase;
Aged;
Alzheimer Disease;
Brain;
Dysarthria*;
Female;
Humans;
Magnetic Resonance Imaging;
Memory;
Neuropsychological Tests
- From:Journal of the Korean Neurological Association
2001;19(2):170-172
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
We report a case of speech disturbance as an unrecognized adverse effect of the selective acetylcholinesterase inhibitor, donepezil. A 79-year-old woman presented with progressive memory disturbance that began 3 years ago. A brain MRI and neuropsychological test suggested that she had Alzheimer's disease. She showed transient dysarthria 14 days after the initiation of donepezil. Isolated speech disturbances were not observed. Clinicians should be alert to the possibility of dysarthria as an adverse effect of donepezil. (J Korean Neurol Assoc 19(2):170~172, 2001)
