The pleiomorphic actions of vitamin D and its importance for children.
10.6065/apem.2013.18.2.45
- Author:
Se Young KIM
1
Author Information
1. Department of Pediatrics, Bundang Jesaeng General Hospital, Daejin Medical Center, Seongnam, Korea. odajulia@dmc.or.kr
- Publication Type:Review
- Keywords:
Vitamin D;
Vitamin D receptor;
Child;
Growth
- MeSH:
Adolescent;
Calcium;
Child;
Chronic Disease;
Developed Countries;
Growth and Development;
Homeostasis;
Humans;
Nutritional Requirements;
Receptors, Calcitriol;
Rickets;
Vitamin D;
Vitamin D Deficiency;
Vitamins
- From:Annals of Pediatric Endocrinology & Metabolism
2013;18(2):45-54
- CountryRepublic of Korea
- Language:English
-
Abstract:
Knowledge regarding the physiological role and dietary requirements of vitamin D has dramatically expanded over the past several decades. The "new" vitamin D is not only a mediator of calcium homeostasis, it also has important immunomodulatory, antimicrobial, and antiproliferative actions. In spite of the interest in vitamin D as a mediator in many chronic diseases of adulthood such as cancer and type II diabetes, less attention has been given to the implications of the new understanding of vitamin D for child and adolescent health. Recently, rickets caused by vitamin D deficiency is resurging in developed countries. Therefore, pharmacokinetic studies and epidemiologic research that incorporates clinical and functional outcomes are needed to clarify the role of vitamin D in growth and development in Korean children and adolescents and to determine vitamin D dietary requirements.
