Patients Presenting with Advanced Human Immunodeficiency Virus Disease: Epidemiological Features by Age Group.
10.3346/jkms.2016.31.2.178
- Author:
Cho Ryok KANG
1
;
Ji Hwan BANG
;
Sung Il CHO
;
Kui Nam KIM
;
Hee jin LEE
;
Bo Yeong RYU
;
Soo Kyung CHO
;
Young Hwa LEE
;
Myoung don OH
;
Jong Koo LEE
Author Information
1. Seoul Center for Infectious Disease Control, Seoul, Korea. roundbirch@gmail.com
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
HIV;
Acquired Immune Deficiency Syndrome;
Late Presentation;
Early Detection;
Seoul Metropolitan City;
Low Education;
Old Age
- MeSH:
Adult;
Age Factors;
CD4 Lymphocyte Count;
Cross-Sectional Studies;
Demography;
Female;
HIV Infections/*diagnosis/*epidemiology;
Humans;
Logistic Models;
Male;
Middle Aged;
Odds Ratio;
Republic of Korea/epidemiology;
Young Adult
- From:Journal of Korean Medical Science
2016;31(2):178-182
- CountryRepublic of Korea
- Language:English
-
Abstract:
We explored factors influencing presentation with advanced human immunodeficiency virus (HIV) disease by age group. Data were derived from a city-wide cross-sectional survey of 759 HIV-infected adults living in Seoul, Korea. The significance of each observed factor was assessed via multivariate logistic regression. Of subjects aged 20-34 years, lower educational level had a positive influence on presentation with advanced HIV disease (adjusted odds ratio [aOR], 2.43; 95% confidence interval [CI], 1.36-4.34); those recently diagnosed with HIV were more likely to be presented with advanced HIV disease (aOR, 3.17; 95% CI, 0.99-10.2). Of the subjects aged 35-49 years, those w ith advanced HIV disease were more likely to have been diagnosed during health check-ups (aOR, 2.91; 95% CI, 1.15-7.32) or via clinical manifestations (aOR, 3.61; 95% CI, 1.39-9.36). Of the subjects aged > or = 50 years, presentation with advanced HIV disease was significantly more common in older subjects (aOR per increment of 5 years, 2.06; 95% CI, 1.32-3.23) and less common among individuals diagnosed with HIV in 2000-2006 (aOR, 0.18; 95% CI, 0.04-0.83). In conclusion, a lower educational level in younger subjects and more advanced age in older subjects positively influence the presentation of advanced HIV disease.