Role of Intranasal Topical Steroid in Pediatric Sleep Disordered Breathing and Influence of Allergy, Sinusitis, and Obesity on Treatment Outcome.
- Author:
Yong Gi JUNG
1
;
Hyo Yeol KIM
;
Jin Young MIN
;
Hun Jong DHONG
;
Seung Kyu CHUNG
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Changwon Hospital, Changwon, Korea.
- Publication Type:Original Article
- Keywords:
Steroid;
Topical administration;
Sleep disorder;
Adenoid;
Pediatrics;
Allergy
- MeSH:
Adenoids;
Administration, Topical;
Child;
Humans;
Hypersensitivity;
Hypertrophy;
Neck;
Obesity;
Pediatrics;
Pregnadienediols;
Prospective Studies;
Quality of Life;
Sinusitis;
Skin;
Sleep Apnea Syndromes;
Sleep Apnea, Obstructive;
Treatment Outcome;
Mometasone Furoate
- From:Clinical and Experimental Otorhinolaryngology
2011;4(1):27-32
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: To evaluate efficacy of short term intranasal corticosteroid (mometasone furoate) treatment in pediatric sleep-disordered breathing (SDB) patients. METHODS: A prospective, observational study was done. A total of 41 children (2-11 years old) were enrolled into this study. All patients received 4-weeks course of mometasone furoate 100 microg/day treatment. They were evaluated at pretreatment and immediately after treatment with obstructive sleep apnea (OSA)-18 quality of life survey and lateral neck X-ray. Also, the assessment of each patients included history, skin prick test or CAP test, and sinus radiography. We compared the OSA-18 survey score and adenoidal-nasopharyngeal (AN) ratio between before and after treatment. RESULTS: Total OSA-18 score and AN ratio decreased significantly after treatment regardless of allergy, sinusitis, and obesity (P=0.003, P=0.006). There was no complication after treatment of mometasone furoate. CONCLUSION: Pediatric SDB patients with adenoid hypertrophy could be effectively treated with 4-weeks course of mometasone furoate. Allergy, obesity, and sinusitis did not affect on the result of treatment.