Effect of artemisinin in treatment of breast cancer
- Author:
Huyen Tich Hoang
- Publication Type:Journal Article
- Keywords:
breast cancer
- MeSH:
Breast Neoplasms;
therapeutics;
artemisinine;
breast;
neoplasms
- From:Journal of Medical Research
2002;20(4):76-77
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Artemisinin, a sesquiterpen lacton, is an active ingredient of the sweet wormwood plant. It is used mostly for malaria. It can kill the cancer cell by following mechanism: endoperoxyd junction of artemisinin degrades haem (containing Fe), after reaction, new generated free radicals akylate and oxygenate protein and lipid, deteriorate macromolecular and kill the parasite without significant adverse effects. Administration of artemisinin derivatives with acceptable dosage and combination with a iron salt can produce potent effect on cancer, especially on breast cancer.
