Impact of Exercise-Based Cardiac Rehabilitation on De Novo Coronary Lesion in Patients With Drug Eluting Stent.
10.5535/arm.2014.38.2.256
- Author:
Hee Eun CHOI
1
;
Byeong Ju LEE
;
Chul KIM
Author Information
1. Department of Rehabilitation Medicine, Inje University Sanggye Paik Hospital, Seoul, Korea. s3163@paik.ac.kr
- Publication Type:Original Article
- Keywords:
Coronary stenosis;
Drug-eluting stents;
Exercise;
Rehabilitation
- MeSH:
Acute Coronary Syndrome;
Coronary Angiography;
Coronary Stenosis;
Drug-Eluting Stents;
Follow-Up Studies;
Humans;
Observational Study;
Percutaneous Coronary Intervention;
Phenobarbital;
Rehabilitation*;
Retrospective Studies;
Stents*
- From:Annals of Rehabilitation Medicine
2014;38(2):256-262
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: To compare the rate of progression of de novo lesion between the cardiac rehabilitation (CR) and control groups. METHODS: This is a retrospective observational study. Patients who received drug-eluting stent (DES) due to acute coronary syndrome were included as subjects. The CR group received eight weeks of early CR program, and sustained a self-exercise program in the homes. The control group was instructed to exercise independently. Nine months after the first insertion of DES, we implemented follow-up coronary angiography, and compared the rate of progression of de novo lesion by quantitative angiographic measurement between the two groups. RESULTS: A total of 81 patients were recruited as subjects to CR group (n=32) or control group (n=49). At nine months, late luminal loss was 0.04+/-0.23 mm in the CR group and 0.00+/-0.31 mm in the control group (p=0.54, observed power=0.10). Late loss was -0.90%+/-9.53% in the CR group and 0.80%+/-11.15% in the control group (p=0.58, observed power=0.05). No target lesion revascularization procedures were needed in the CR group, while two in the control group (p=0.25). In the CR group, mean VO2max was significantly improved from 24.36+/-5.00 to 27.68+/-5.24 mL/kg/min (p<0.001). CONCLUSION: We could not observe a statistically significant difference in the progression rate of de novo lesion between the CR and control groups. Thus the current amount of nine months exercise-based CR program does not seem to have a distinct impact on the retardation of de novo coronary lesion in patients who received percutaneous coronary intervention with DES.
