Double-blind, Placebo-controlled, Multi-center Study for Therapeutic Effects of Mountain Panax Ginseng C.A. Meyer Extract in Men with Erectile Dysfunction: a Preliminary Report.
- Author:
Hong Sik KIM
1
;
Seung Hyo WOO
;
Shunghwan JO
;
Eun Joo HAHN
;
Nae Young YOUN
;
Hyung Lae LEE
Author Information
1. Department of Urology, Chungnam National University Medical School, Daejeon, Korea.
- Publication Type:Multicenter Study ; Randomized Controlled Trial ; Original Article
- Keywords:
Erectile dysfunction;
Panax ginseng C.A. Meyer;
Penis
- MeSH:
Blood Cell Count;
Double-Blind Method;
Erectile Dysfunction*;
Hematologic Tests;
Humans;
Liver;
Male;
Panax*;
Penis;
Surveys and Questionnaires;
Urinalysis
- From:Korean Journal of Andrology
2006;24(2):84-88
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We investigated the effect of 100-year-old mountain ginseng(Panax ginseng C.A. Meyer, PG-CAM) extract on patients with erectile dysfunction(ED). MATERIALS AND METHODS: A total of 35 patients with ED(23 patients in PG-CAM administration group, 12 in placebo group) were enrolled in this double-blind study. The drug was administered for 12 weeks. Before and after administration, patients took the self-administered IIEF-5 questionnaire and were tested for serum hormone levels(testosterone, LH, FSH, estradiol), complete blood count, liver and renal function test, and urinalysis. RESULTS: The IIEF-5 scores for the placebo group were 19.7+/-2.3 and 19.9+/-3.6 before and after treatment, respectively. For all patients taking PG-CAM, IIEF-5 scores increased 18.1+/-5.6 to 20.2+/-4.5. For those patients with initial scores below 17, IIEF-5 scores increased from 12.4+/-6.2 to 19.7+/-6.7. These results indicate that PG-CAM may increase erectile function in ED patients, particularly those with poor erection. No changes were detected in hormonal levels or blood tests. No toxic side effect were reported. CONCLUSIONS: IIEF-5 score improved significantly in ED patients treated with PG-CAM, suggesting that PG-CAM extract could be a treatment candidates for ED.
