The Addition of Subarachnoid Fentanyl to Hyperbaric Bupivacaine with Morphine for Cesarean Section.
10.4097/kjae.1994.27.12.1779
- Author:
Soo Chang SON
1
;
Seok Hwa YOON
;
Yong Sup SHIN
;
Hae Ja KIM
;
Se Jin CHOI
Author Information
1. Department of Anesthesiology, Chungnam National University, College of Medicine, Daejon, Korea.
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Spinal Anesthesie;
Bupivacaine;
Fentanyl;
Morphine
- MeSH:
Analgesia;
Anesthesia, Spinal;
Apgar Score;
Bupivacaine*;
Cesarean Section*;
Female;
Fentanyl*;
Humans;
Hypotension;
Incidence;
Infant, Newborn;
Morphine*;
Narcotics;
Needles;
Pregnancy;
Pruritus;
Respiratory Insufficiency;
Sensation;
Visceral Pain
- From:Korean Journal of Anesthesiology
1994;27(12):1779-1785
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
To investigate the effect of intrathecal fentanyl,36 ASA physieal status 1 or 2 parturients who underwent cesarean section with apinal anesthesis using 0.25% bupivacaine in 5.0% dextroae with 0.25mg morphine were studied. Patients were randomly allocated to receive either saline 0.2ml (group 1, n=17) or fentanyl 10ug(group 2, n=19) in 3.525ml volume mixed with the bupivacaine with morphine. Spinal anesthesia was performed in sitting position using a 25 guage spinal needle. At the completion of injection, patients immediately turned supine with left uterine diaplacement. There was no statistically significant difference in the incidence of the hypotension between groups. The progress of sensory and motor blocks was similar in the two groups. The times from drug injection ta the onset to maximal sensory blockade and complete motor blockade, complete recovery of sensation and motor power were not different between groups. post delivery,the incidence of visceral pain were significantly less in group 2, as 2 of 19 patients(10%) in group 2 compared to 8 of 17 patients(47%) in group 1(p< 0.05). The effective analgesia time was no significant different: 31.7+/-2.5 hour in group 1 compared to 28.6+/-5.6 hour in Group 2. The ineidence of patients not requiring narcotics until discharge was similar in two groups. No patient showed any evidence of respiratory depression. The incidence of other side effects,such as nausea,vomiting and pruritus was not different between groups. No neonate had an Apgar score below 7.
