Correlation of Narrow Band Imaging with Magnifying Colonoscopy and Histology in Colorectal Tumors.
- Author:
Hee Yong YOO
1
;
Moon Sung LEE
;
Bong Min KO
;
Hee Kyung KIM
;
Hyung Su AHN
;
Seung Hyo HAN
;
Jun Yong BAE
;
Seul Ki MIN
;
Jong Chan LEE
;
Chang Beom RYU
Author Information
1. Department of Internal Medicine, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea. mslee@schmc.ac.kr
- Publication Type:Original Article
- Keywords:
Narrow band imaging;
Magnifying colonoscopy;
Histology;
Colorectal tumor
- MeSH:
Capillaries;
Colon;
Colonoscopy;
Colorectal Neoplasms;
Humans;
Narrow Band Imaging;
Polyps;
Sensitivity and Specificity
- From:Clinical Endoscopy
2011;44(1):44-50
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Narrow band imaging (NBI) is a new technique that uses optical filters for imaging of mucosal morphology. The aim of this study was to correlate findings of NBI with magnifying colonoscopy and histology for prediction of neoplastic colorectal lesion. METHODS: Between September 2005 and December 2007, 107 colon polyps from 68 patients were detected by conventional colonoscopy and subsequently evaluated by NBI with magnifying colonoscopy and analyzed for a pit pattern and a capillary pattern. More analysis was done regarding thickness and irregularity of capillary features. RESULTS: Pit pattern with NBI magnification to discriminate between neoplastic and non-neoplastic lesions had a sensitivity of 88.9% and a specificity of 87.5%; capillary pattern yielded test performance characteristics of 91.9% and 87.5%. In respect of capillary thickness, invisible capillaries were found significantly more often in hyperplastic lesions. All thick capillaries were found in neoplastic polyps, and found significantly more often in carcinomas with submucosal massive invasion (sm-m) (p<0.01). In respect of capillary irregularity, invisible capillaries were found significantly more often in hyperplasic lesions, and severely irregular capillaries were found significantly more often in sm-m lesions (p<0.01). CONCLUSIONS: Observation of capillary thickness and irregularity by NBI magnification is useful for correlating histological grade with carcinoma, especially with depth of submucosal invasion.
