Successful Chemotherapy Following Autologous Stem Cell Transplantation in Multiple Myeloma and Multi-organ Dysfunction with Infiltration of Eosinophils: A Case Report.
- Author:
Ho Sup LEE
1
;
Lee Chun PARK
;
Seong Hoon SHIN
;
Sang Uk LEE
;
Hee Kyung CHANG
;
Bang HUH
;
Gyoo Sik JUNG
;
Mi Hyang KIM
;
Yang Soo KIM
Author Information
1. Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea. towersue@hotmail.com
- Publication Type:Case Report
- Keywords:
Eosinophilia;
Multiple myeloma;
Autologous transplantation
- MeSH:
Adult;
Eosinophilia;
Eosinophils;
Hematopoietic Stem Cells;
Humans;
Hypereosinophilic Syndrome;
Multiple Myeloma;
Stem Cell Transplantation;
Stem Cells;
Transplantation, Autologous
- From:Cancer Research and Treatment
2011;43(3):199-203
- CountryRepublic of Korea
- Language:English
-
Abstract:
Eosinophils are derived from hematopoietic stem cells. Peripheral blood eosinophilia is defined as an absolute eosinophil count of > or =0.5x10(9)/L. Eosinophilia is classified into primary or clonal eosinophilia, secondary eosinophilia, and idiopathic categories including idiopathic hypereosinophilic syndrome. Both hematopoietic and solid neoplasms may be associated with peripheral blood eosinophilia, but multiple myeloma is rarely associated with eosinophilia. We now report the case of a 31-year-old man with multiple myeloma associated with marked eosinophilia who developed multiple organ dysfunction with infiltration of eosinophils. He recovered after treatment with chemotherapy followed by autologous stem cell transplantation.
