Spermatocytic Seminoma With Sarcoma: An Indication for Adjuvant Chemotherapy in Localized Disease.
10.4111/kju.2013.54.12.884
- Author:
David WETHERELL
1
;
Nathan LAWRENTSCHUK
;
Dennis GYOMBER
Author Information
1. Department of Urology, University of Melbourne, Austin Hospital, Heidelberg, Australia. drwetherell@doctors.org.uk
- Publication Type:Case Report
- Keywords:
Orchiectomy;
Sarcoma;
Seminoma;
Testicular neoplasms;
Testis
- MeSH:
Adult;
Chemotherapy, Adjuvant*;
Humans;
Male;
Neoplasms, Germ Cell and Embryonal;
Orchiectomy;
Prognosis;
Sarcoma*;
Seminoma*;
Testicular Neoplasms;
Testis
- From:Korean Journal of Urology
2013;54(12):884-887
- CountryRepublic of Korea
- Language:English
-
Abstract:
Spermatocytic seminoma (SCS) with sarcoma is an extremely rare testicular tumor with only 11 cases previously described in the literature. We present the 12th case of SCS with sarcoma in a 29-year-old male. SCS itself is an uncommon germ cell tumor with a relatively indolent clinical course that mostly affects males around the fifth decade of life. Sarcomatous differentiation of SCS occurs in 5% to 6% of cases and correlates with a higher possibility of metastatic disease and a poor prognosis. Clinically, this tumor manifests as a slow-growing testicular mass often with an accelerated period of secondary growth. After a concise review of the literature, we conclude that SCS with sarcoma should be treated by radical inguinal orchidectomy with strong consideration given to adjuvant chemotherapy.
