A Case of Acute Myelocytic Leukemia developed the Cutaneous Granulocytic Sarcoma (Chloroma) and Leukemia Cutis.
- Author:
Sang Boo SHIN
1
;
Dong Won LEE
;
Jun Young LEE
;
Baik Kee CHO
Author Information
1. Department of Dermatology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Leukemia cutis;
Granulocytic sarcoma;
Acute myelocytic leukemia;
Myelodysplastic syndrome
- MeSH:
Abdomen;
Biopsy;
Collagen;
Cytoplasm;
Female;
Granulocyte Precursor Cells;
Humans;
Leukemia*;
Leukemia, Myeloid, Acute*;
Middle Aged;
Myelodysplastic Syndromes;
Peroxidase;
Sarcoma, Myeloid*;
Upper Extremity
- From:Korean Journal of Dermatology
2000;38(7):933-936
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Cutaneous granulocytic sarcoma are rare extramedullary tumor composed of immature leukemic cells of the myeloid series. It has a characteristic greenish color caused by myeloperoxidase in the granulocytic cells. 58-year-old female patient who had been diagnosed as acute myelocytic leukemia presented multiple, variable sized, tender brown-pigmented nodules, papules and plaques on the abdomen and both upper extremities for about 4 weeks. An incision biopsy of the large subcutaneous nodule on her abdomen showed a dense dermal infiltrate of immature myeloblastic cells with pleomorphic hyperchromatic vesicular nuclei and conspicuous nucleoli. A punch biopsy of the other small papule on her abdomen showed an infiltrate of granulocytic cells with round hyperchromic nuclei and granular acidophilic cytoplasm, between the dermal collagen bundles. We present a case of the cutaneous granulocytic sarcoma (chloroma) with coexistent leukemia cutis in acute myelocytic leukemia developed from myelodysplastic syndrome.
