Effect of Epinephrine or Pilocarpine on me Ocular Blood Flow.
- Author:
Kyoo Won LEE
1
Author Information
1. Department of Ophthalmology, College of Medicine, Yeungnarn University, Daegu, Korea.
- Publication Type:Original Article
- Keywords:
Epinephrine;
Ocular blood flow(OBF) Ocular pulse amplitude(PA);
Ocular vas cular resistance;
Pilocarpine
- MeSH:
Choroid;
Epinephrine*;
Haplorhini;
Macaca fascicularis;
Pilocarpine*;
Vascular Resistance
- From:Journal of the Korean Ophthalmological Society
1990;31(6):767-771
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The ocular vascular resistance of the ciliary choroidal network has been investigated on measurements of pulse amplitude(PA). The ocular pulse is derived from the ciliary choroidal blood flow which account for more than 90% of the total ocular blood flow(OBF). In 5 normal Cynomolgus monkeys with topical application(50 micro l) of 2% epinephrine, the PA revealed a significant reduction(0.32 +/- 0.06mmHg, mean +/- SEM, p<0.01). In the other 5 normal Cynormlgus monkeys with 4% pilocarpine, the PA revealed no significant increment(0.32 +/- 0.15mmHg, mean +/- SEM, p<0.10) by the OBF system. These results suggest that topical application of epinephrine produces a significant reduction of OBR but pilocarpine produces a mild increment of OBF.
