Characterization of Peroxiredoxins in the Gray matter in the spinal cord after Acute Immobilization Stress.
- Author:
Nam Hyun PAEK
1
;
Seung Soo KWAK
;
Dong Seok LEE
;
Young Ho LEE
Author Information
1. Department of Surgery, SUN General Hospital, Korea.
- Publication Type:Original Article
- Keywords:
Peroxiredoxins;
Acute immobilization stress
- MeSH:
Animals;
Brain;
Catalase;
Cell Membrane;
Cytoplasm;
Dendritic Cells;
Immobilization*;
Mice;
Neurodegenerative Diseases;
Neurons;
Neurotransmitter Agents;
Peroxiredoxins*;
Reactive Oxygen Species;
Signal Transduction;
Spinal Cord*
- From:Journal of the Korean Society of Traumatology
2006;19(2):105-112
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Many stresses produce reactive oxygen species and bring about mechanism of antioxidant reaction. Cytokine and a neurotransmitter through the cell membrane, as well as signal transduction through the cell membrane, are used for various pathological condition of the brain, such as neurodegenerative disease. There are several antioxidant enzymes in cells (superoxcide dismutase, glutathion peroxidasae, peroxiredoxin catalase, etc.) METHODS: This study used single- or double-label immunohistochemical techniques to analyze mouse spinal neuron cells expressing Prx I and Prx III after acute mobilization stress. RESULTS: Prx I was observed in dendritic cell of the gray matter of the spinal cord, and Prx III was observed in the cytoplasm of the GM of the spinal cord. CONCLUSION: The results of this study will help to explain differences of expression in the distributions of the peroxiredoxin enzymes of the spinal cord.
