The Usefulness of Stress Perfusion MR using Steady State Free Precession Sequence for Depiction of Significant Coronary Artery Stenosis.
10.3348/jkrs.2007.56.1.25
- Author:
Se Yeong CHUNG
1
;
Sang Il CHOI
;
Dong Hoon KIM
;
Hyuk Jae CHANG
;
Dong Ju CHOI
;
Cheong LIM
;
Whal LEE
;
Jae Hyung PARK
Author Information
1. Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea. drsic@radiol.snu.ac.kr
- Publication Type:Original Article
- Keywords:
Myocardium;
Magnetic resonance (MR);
Coronary vessels, diseases
- MeSH:
Constriction, Pathologic;
Coronary Angiography;
Coronary Artery Disease;
Coronary Stenosis*;
Coronary Vessels*;
Dyspnea;
Flushing;
Humans;
Magnetic Resonance Imaging;
Myocardium;
Perfusion Imaging;
Perfusion*;
Sensitivity and Specificity;
Thorax
- From:Journal of the Korean Radiological Society
2007;56(1):25-31
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate the technical performance of stress myocardial perfusion magnetic resonance (MR) imaging using saturation-recovery steady-state free precession (SR- SSFP) and to assess the diagnostic accuracy of this examination for depiction of significant coronary artery stenosis. MATERIALS AND METHODS: 167 patients underwent stress myocardial perfusion MR imaging at rest and adenosine-induced stress by using a 1.5-T cardiac MR imaging unit. The first-pass MR perfusion was performed using SR-SSFP sequence. Coronary angiography was performed in 113 patients. Image analysis was performed to compare the diagnostic accuracy of MR imaging with that of coronary angiography. RESULTS: During the MR examination, minor side effects of adenosine-induced stress occurred, most commonly chest discomfort (29%), followed by dyspnea (4%), and facial flushing (0.8%). The overall sensitivity of MR imaging for depicting at least one coronary artery with significant stenosis was 91%. The sensitivities of MR imaging for depiction of stenoses were as follows: 80% for single-vessel stenosis, 81% for double-vessel stenosis, and 100% for triple-vessel stenosis.. The specificity of MR imaging for identification of patients with significant coronary artery stenosis was 78%. CONCLUSION: Stress myocardial magnetic resonance (MR) perfusion imaging using SR-SSFP sequence is safe and useful for the detection of significant coronary artery disease.
