Congenital Anomalies Observed by Autopsies at the Seoul National University Children's Hospital.
- Author:
Jin Haeng CHUNG
;
Jeong Wook SEO
;
Chong Jai KIM
;
Chul Woo KIM
;
Je G CHI
- Publication Type:Original Article
- Keywords:
Congenital anomaly;
Autopsy;
Perinatal mortality;
cardiovascular disease
- MeSH:
Autopsy*;
Cardiovascular Diseases;
Cardiovascular System;
Child;
Humans;
Incidence;
Infant;
Infant, Newborn;
Musculoskeletal System;
Nervous System;
Parturition;
Perinatal Mortality;
Retrospective Studies;
Seoul*
- From:Korean Journal of Pathology
1997;31(2):93-99
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A retrospective analysis was performed on the 968 cases of fetal or pediatric autopsies over five year period (1990-1994), at the Seoul National University Children's Hospital. Age/mode distribution of cases were artificial abortus(30.6%), spontaneous abortus(12.0%), stillbirth(21.9%), neonates(29%), infants(2.8%) and children(0.9%). Male/female ratio was 1.21. Overall incidence of congenital anomalies was 60.8% and 34.0% of all cases had anomalies involving multiple organ systems. Percentage of cases with any anomaly was 71.6% in artificial abortus, 35.3% in spontaneous abortus, 59% in still births, 65.5% in neonates and 38.9% in infant and children. Common organ systems involved were the cardiovascular system (39.0%), musculoskeletal system (23.6%), nervous system (22.6%), gastrointestinal system (19.9%), and urinary system (14.6%). From these results, we found that the congenital anomalies were most significant diseases of the perinatal period and the cardiovascular anomalies were the most common anomalies of them.
