A Case of Behcet's Disease with Splenic Infarction.
- Author:
Jang Han JUNG
1
;
Min Kyu KANG
;
Han Na LEE
;
Mi Hye KWON
;
Chung Il JOUNG
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Konyang University College of Medicine, Daejeon, Korea. cij1221@kyuh.co.kr
- Publication Type:Case Report
- Keywords:
Behcet's disease;
Splenic infarct;
Arteritis
- MeSH:
Abdominal Pain;
Adult;
Arteritis;
Autoimmune Diseases;
Azathioprine;
Blood Sedimentation;
C-Reactive Protein;
Flank Pain;
Heparin;
Heparin, Low-Molecular-Weight;
Hospitalization;
Humans;
Methotrexate;
Prednisolone;
Splenic Artery;
Splenic Infarction;
Thrombosis
- From:Korean Journal of Medicine
2011;81(1):126-129
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Behcet's disease is a multisystem autoimmune disease with vasculitic features, and major vascular involvement occurs in 7.7-60% of patients. Venous lesions are more common than arterial lesions and arterial thrombotic events are relatively rare. We report a patient with Behcet's disease who developed a splenic infarct associated with splenic thrombotic arteritis. A 44-year-old man who had been diagnosed with Behcet's disease 5 years earlier presented with left flank pain lasting for 5 days. Laboratory tests revealed an elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). Computed tomography (CT) and three-dimensional CT showed a wedge-shaped splenic infarct and thrombus in the splenic artery. We treated him with low-molecular-weight heparin and prednisolone. The symptoms improved within 6 days of hospitalization, after which we stopped the heparin and added methotrexate and azathioprine. Splenic infarct should be ruled out if patients with Behcet's disease complain of new left-sided abdominal pain.