Late Adverse Reaction to Iodixanol (Visipaque(R)).
- Author:
Cha Young KIM
1
;
Hee Jin KIM
;
Moon Jin KIM
;
Yeojin KANG
;
Hyun Jung KIM
;
Se Ho CHANG
;
Dong Jun PARK
Author Information
1. Department of Internal Medicine, Gyeongsang National University Hospital, Jinju, Korea. drpdj@korea.com
- Publication Type:Case Report
- Keywords:
Iodixanol;
Hypersensitivity;
Adverse reaction
- MeSH:
Abdomen;
Angioedema;
Edema;
Exanthema;
Humans;
Hypersensitivity;
Proteinuria;
Pruritus;
Skin;
Thorax;
Triiodobenzoic Acids;
Urticaria
- From:Korean Journal of Medicine
2011;81(1):130-134
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Late adverse reactions to iodinated contrast medium are defined as reactions occurring 1 hour to 1 week after contrast medium injection. The majority of late adverse reactions are cutaneous reactions, and include itching, maculopapular rash, urticaria, erythematous patches, and angioedema. We report a patient with an iodixanol (Visipaque(R))-induced late adverse reaction. She was admitted for evaluation of nephrotic range proteinuria and edema. Abdomen and chest enhanced computed tomography was performed as a malignancy work-up. Sixteen hours after radiocontrast exposure, her entire body felt itchy. A maculopapular rash was first detected on her back and abdomen 24 hours after exposure, and spread over her entire body, including her face. Her skin lesions resolved completely in 5 days after administering steroid and antihistamine. We should consider late adverse reactions of iodinated contrast medium when we detect skin lesions late after radiocontrast use.
