The Up-to-date Informations of Progesterone Supplementation for Prevention of Preterm Birth.

Author: Hyun Jin CHO ¹
Author Information

1. Department of Obstetrics and Gynecology, College of Medicine, Inje University, Haeundae Paik Hospital, Busan, Korea. lory1202@naver.com
Publication Type:Review
Keywords: Cervical length; Preterm birth; Preterm labor; Progesterone
MeSH: Cervix Uteri; Female; Humans; Infant; Infant Mortality; Obstetric Labor, Premature; Pregnancy; Premature Birth; Progesterone; Tocolysis
From:Kosin Medical Journal 2013;28(1):1-6
CountryRepublic of Korea
Language:English
Abstract: Preterm birth (PTB) remains a major cause of neonatal mortality and morbidity, despite improvements in tocolytic treatment and neonatal care. Progesterone (17a-hydroxyprogesterone) produced naturally or synthetically can prevent PTB when applied vaginally and orally. Progesterone use may be a safe and cost-effective option in cases of singleton pregnancy with prior PTB, asymptomatically short cervix and arrested preterm labor.