A Quantitative Analysis for Pre-processing Algorithm of Aberration Chromosome Observation.
- Author:
Gye Rok JEON
1
;
Yong Hoon CHANG
;
Sang Hee EOM
Author Information
1. Department of Biomedical Engineering, College of Medicine, Pusan National University, Korea. grjeon@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Chromosome;
Preprocessing Algorithm;
Feature Parameter
- MeSH:
Chromosome Aberrations;
Chromosomes, Human;
Classification;
Humans
- From:Journal of Korean Society of Medical Informatics
2002;8(1):63-70
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The task of chromosome analysis is the classification of human chromosomes. The feature parameter of chromosome is very important information for chromosome analysis. The special preprocessing algorithm is required to extracting them. In this paper, we performed quantitative analysis for preprocessing algorithm of observation of chromosomal aberrations. Two algorithms is used MAT and reconstruction. The morphological feature parameters were centromeric index(C.I.), relative length ratio(R.L.), relative area ratio(R.A.) and chromosome length(C.L.), and the density and width profiles. The reconstruction of chromosome images by this reconstruction algorithm was appeared as effective algorithms to observe and extract chromosome parameter.
