A Case Report of Sepsis by Extended-Spectrum beta-Lactamase Producing Escherichia Coli.
10.4082/kjfm.2010.31.5.384
- Author:
Seung Beom LEE
1
;
Choon Ok KIM
;
Hee Cheol KANG
Author Information
1. Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea. kanghc@yuhs.ac
- Publication Type:Case Report
- Keywords:
Acute Pyelonephritis;
Extended Spectrum beta-Lactamase;
Escherichia Coli
- MeSH:
Adult;
Anti-Bacterial Agents;
beta-Lactamases;
Ciprofloxacin;
Escherichia;
Escherichia coli;
Female;
Humans;
Monobactams;
Prognosis;
Pyelonephritis;
Sepsis
- From:Korean Journal of Family Medicine
2010;31(5):384-389
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The overall prognosis of acute pyelonephritis is good, but the infections by extended spectrum beta-lactamase (ESBL) producing Escherichia coli (E.coli) cause poor responses to empirical antibiotic treatment, and consequently increase mortality. ESBL can hydrolyze the antibiotics with a beta-lactam ring and confer resistance to oxyimino-cephalosporins and monobactams. If the patient shows poor responses to empirical antibiotics or severe septic conditions, physicians must switch the antibiotics to other antibiotics covering resistant strains without delay. We report a case of acute pyelonephritis by extended-spectrum beta-lactamase producing E.coli in a 29-year-old woman who was empirically treated with oral ciprofloxacin as an initial treatment, but progressed to sepsis.
