A Case of Intraperitoneal Immunoglobulin G4-related Inflammatory Pseudotumor.
10.4166/kjg.2012.60.4.258
- Author:
In Ho MOH
1
;
Jin Bae KIM
;
Su Rin SHIN
;
Sung Won JUNG
;
Sang Hoon PARK
;
Jeong Won KIM
;
Mi Kyung SHIN
;
Myung Seok LEE
Author Information
1. Department of Internal Medicine, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. jbkim87@hallym.or.kr
- Publication Type:Case Reports
- Keywords:
IgG4-related disease;
Immunoglobulin G4;
Inflammatory pseudotumor;
Intraperitoneal tumor
- MeSH:
Aged, 80 and over;
C-Reactive Protein/analysis;
Female;
Granuloma, Plasma Cell/*diagnosis/pathology/surgery;
Humans;
Immunoglobulin G/*blood;
Plasma Cells/metabolism;
Positron-Emission Tomography;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2012;60(4):258-261
- CountryRepublic of Korea
- Language:English
-
Abstract:
The term inflammatory pseudotumor (IPT) has been used to describe inflammatory and fibrosing tumoral processes of an undetermined cause that may involve a variety of organ system. IgG4-related disease is a newly recognized fibroinflammatory condition characterized by IgG4-producing plasma cell expansion in affected organs and, often but not always, elevated serum IgG4 concentrations. IgG4-related IPTs, a subtype of IPT, are characterized by dense infiltration of IgG4-positive plasma cells and stromal fibrosis. The association between inflammatory pseudotumor and IgG4 was first reported with a regard to sclerosing pancreatitis. Despite there are many reports on intraperitoneal IPTs including both cellular and lymphoplasmacytic type, only a few cases have been confirmed to be IgG4-related. We experienced a case of intraperitoneal IgG4-related inflammatory pseudotumor in an 83-year-old woman presenting with epigastric pain and malaise. Surgical specimens revealed an IgG4-related inflammatory pseudotumor.
