Ulcerative Infantile Hemangioma Treated with Topical Timolol.
- Author:
Young Woon PARK
1
;
Kkot Bora YEOM
;
Kyu Han KIM
Author Information
1. Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea. Kyuhkim@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Beta blocker;
Hemangioma;
Timolol;
Topical treatment
- MeSH:
Arrhythmias, Cardiac;
Bradycardia;
Bronchial Spasm;
Hemangioma;
Hypoglycemia;
Hypotension;
Propranolol;
Timolol;
Ulcer
- From:Korean Journal of Dermatology
2012;50(10):880-883
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Therapeutic options for infantile hemangioma are limited. The nonselective beta-adrenergic receptor antagonist propranolol is an effective therapy for infantile hemangiomas. However, systemic propranolol carries a risk of serious side effects, including bradycardia, hypoglycemia, arrhythmias, hypotension and bronchospasm. Recently, treatment of infantile hemangioma with topical timolol (nonselective beta-blocker similar to propranolol) has been reported. We treated successfully the perineal ulcerative hemangioma with topical timolol. We believe that timolol is a safe and effective topical agent and should be strongly considered as one of good therapeutic options for hemagnioma.