Two Cases of Generalized Granuloma Annulare Treated with PUVA.
- Author:
Hyung Yoon PARK
1
;
Tae Ho PARK
;
Moon Chul JEONG
;
Jae Hak YOO
;
Kea Jung KIM
Author Information
1. Department of Dermatology, Kangbuk Samsung Hospital, College of Medicine, Sungkyunkwan University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Generalized granuloma annulare;
PUVA
- MeSH:
Arm;
Chloroquine;
Collagen;
Dapsone;
Dermis;
Giant Cells;
Granuloma Annulare*;
Granuloma*;
Hand;
Histiocytes;
Humans;
Injections, Intralesional;
Lower Extremity;
Lymphocytes;
Middle Aged;
Shoulder;
Solar System;
Upper Extremity
- From:Korean Journal of Dermatology
2001;39(4):454-458
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Granuloma annulare is a benign granulomatous disease which has an unknown etiology and it is represented by typical annular lesions. Recently various therapeutic modalities have been suggested such as intralesional injections of steroid, chloroquine, dapsone, surgical excision and so on. But any satisfactory result has not been reported yet. In the first case, a 65 year-old-man, Polycyclic, erythematous patches with raised edges were noted on the upper arm spreading to the trunk and both lower extremities for the past 3 years. In the second case, a 63-year-old man, numerous match-head sized skin-colored papules were detected on the sun exposed area such as both shoulders, upper extremities and hands dorsum for the past 3 months. On the histological examination of back, hands dorsum respectively, incomplete degeneration of collagen bundles surrounded by lymphocytes, histiocytes in a palisade pattern and a few giant cells were found in the dermis. Two patients were treated with systemic PUVA, one for 2 months and the other, 4 months.
