A Case of Systemic Lupus Erythematosus Presented as Pseudotumor Cerebri Syndrome.
- Author:
Seong Hwan AHN
1
;
Jae Jin LEE
;
Jin Ho KIM
;
Won Young JUNG
;
Joon ROH
;
Dong Gyu KIM
;
Hee Kwan KOH
Author Information
1. Department of Neurology, Chosun University Medical College, Kwangju, Korea.
- Publication Type:Case Report
- Keywords:
Pseudotumor cerebri syndrome;
Systemic lupus erythematosus
- MeSH:
Absorption;
Arachnoid;
Brain;
Central Nervous System;
Diagnosis;
Female;
Headache;
Humans;
Intracranial Pressure;
Lupus Erythematosus, Systemic*;
Nervous System;
Papilledema;
Pseudotumor Cerebri*;
Psychotic Disorders;
Seizures;
Young Adult
- From:The Journal of the Korean Rheumatism Association
2000;7(4):420-425
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pseudotumor cerebri syndrome is characterized clinically by raised intracranial pressure without ventriculomegaly. Several conditions known to interfere with CSF absorption pathways at the level of the arachnoid villi can produce the pseudotumor cerebri syndrome. Systemic lupus erythematosus (SLE) is an autoimmune, inflammatory and chronic disorder characterized by multi-organ involvement including the nervous system. Clinical evidence of central nervous system involvement includes headache, seizure, psychosis and altered mental status. However, pseudotumor cerebri syndrome has been reported infrequently as a primary feature of central nervous system involvement or a complication of SLE. A 19 year-old female was admitted with seizure preceded by headache and blurred vision. Ophthalmoscopic examination showed papilledema. The diagnosis of pseudotumor cerebri syndrome was confirmed by increased intracranial pressure(>550mmH2O) in the absence of any abnormal radiological findings of the brain. We described a 19-year-old girl whose first clinical manifestation was pseudotumor cerebri syndrome, which was diagnosed as SLE later. Therefore pseudotumor cerebri syndrome may be the part of the spectrum of clinical manifestation of SLE.
